Funded Projects

PRINCIPAL INVESTIGATORS AND CURRENTLY FUNDED PROJECT TITLES
Professor Charles Campbell Link	Clonal methylation profiling of morphologically normal mucosa as a risk marker of colitis-associated colorectal neoplasia (CACRN)	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Professor Peter Hamilton Link	The Northern Ireland Virtual Tissue Archive (NIVTA)	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Professor Paul Harkin Link	To develop and validate a test for the diagnosis and prediction of response to therapy in the BRCA1 deficient/basal sub type of breast cancer	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Professor Patrick Johnston Link	Expression profiling of circulating colorectal cancer (CRC) epithelial cells: Clinical Relevance	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Professor Liam Murray Link	The role of insulin growth factor axis and folate metabolism in the oesophageal inflammation, metaplasoa, adenocarcinoma sequence	Epidemiology Research Group Mulhouse Building, RVH Queen's University Grosvenor Road Belfast, BT12 6BJ

PRINCIPAL INVESTIGATORS AND PREVIOUSLY FUNDED PROJECT TITLES
Professor Anthony Bjourson Link	Genetic screening in breast and breast/ovarian cancer families	Biomedical Sciences Research Institute University of Ulster Cromore Road Coleraine, BT52 1SA
Professor Charles Campbell Link	Pathways of inflammation associated oncogenesis of the colon	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Professor Stephen Downes Link	Late cycle checkpoint defects and cancer (2001- 2006)	School of Biomedical Sciences University of Ulster Cromore Road Coleraine, BT52 1SA
Dr Anna Gavin Link	Long term follow-up of middle-aged men with elevated prostatic specific antigen levels: a population based study	Room 1.37 Mulhouse Building, Block 5, RVH Queen's University Grosvenor Road Belfast, BT12 6BJ
Professor Peter Hamilton Link	The role of machine vision and computerised expert systems in the diagnosis and prognosis of cancer	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Professor Paul Harkin Link	Functional analysis of the BRCA1 tumour suppressor	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Professor David Hirst Link / Professor Stephanie McKeown Link	Enhancement of antitumour efficacy by targeting tumour-specific micro-environmental factors	School of Pharmacy Queen's University Belfast / School of Biomedical Sciences University of Ulster
Dr Alan Hounsell Link	The validation and integration of (18FDG) PET-CT functional data into the radiotherapy treatment planning process for non-small cell lung cancer	Medical Physics Agency Northern Ireland Cancer Centre Lisburn Road Belfast, BT9 7AB
Dr Brian Johnston Link	Oesophageal adenocarcinoma in Barrett's oesophagus: contribution of the Northern Ireland Barrett's Register and mathematical modelling	Consultant Gastroenterologist Room 75, East Wing The Royal Hospitals NHS Trust Belfast, BT12 6BA
Professor Patrick Johnston Link	Characterisation and clinical significance of TS regulated signalling pathways	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Professor Terry Lappin Link	The pathogenesis and treatment of anaemia in cancer	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Professor Helene McNulty Link / Professor Sean Strain Link	Folate status and carcinogenesis	School of Biomedical Sciences Cromore Road University of Ulster Coleraine, BT52 1SA
Dr Tracy Robson Link	Further characterisation of a novel gene, DIR-1, and other stress response genes with a potential role in radio and chemosensitivity	School of Pharmacy Queen's University Belfast Medical Biology Centre 97 Lisburn Road Belfast, BT9 7BL
Professor Ian Rowland Link	Evaluation of the biological activity of faecal water as a biomarker for colon cancer risk	School of Biomedical Sciences University of Ulster Cromore Road Coleraine, BT52 1SA
Dr Hilary Russell Link	Characterisation of a novel candidate ovarian tumour suppressor gene	Centre for Cancer Research and Cell Biology Queen's University Belfast A Floor, Belfast City Hospital Lisburn Road Belfast, BT9 7AB
Dr Hendrik van den Berg Link	Discovery of potential anti-cancer drugs derived from natural products and by rational design	Centre for Cancer Research and Cell Biology Queen's University Belfast U Floor, Belfast City Hospital Lisburn Road Belfast, BT9 7AB
Dr Colum Walsh Link	Epigenetic gene silencing in cancer	School of Biomedical Sciences University of Ulster Cromore Road Coleraine, BT52 1SA

PELECTED PRINCIPAL INVESTIGATORS* AND NOMINATED PROJECTS / FUNDERS
Dr Mohamed El-Tanani Link	Role of PEA3 transcription factor in osteopontin (OPN) mediated breast cancer metastasis (China Fellowship Scheme; Cancer Research UK)	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Dr Sandra Irvine Link	Translational Research Laboratory Elimination of Leukaemia Fund, London (2003-2007)	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Professor Valerie McKelvey-Martin Link	Delineation and Exploitation of the Molecular Characteristics of Cancer Cell Radiosensitivity to Predict the Radiation Response of Tumours. Cancer Research UK, London Sept 2004 - 2007	Biomedical Sciences Research Institute University of Ulster at ColeraineColeraine BT52 1SA
Professor Kevin Prise Link	Targeted radiation studies in cell and tissue models	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Dr Christopher Scott Link	'Development of High-Throughput in vitro Expression and Capture Methodologies for the Identification and Characterisation of Proteases'. C Scott and B Walker. BBSRC	School of Pharmacy, 97 Lisburn Road Belfast BT9 7BL
Dr Kate Williamson Link	The significance of S100A4 and novel candidate epithelial mesenchymal transition (EMT) markers as indicators of metastatic potential in transitional cell carcinoma of the bladder TCCB. North/South Grant, R&D Office/HRB	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL
Dr Richard Wilson Link	Director of NCRN funded Clinical Trials Unit	Centre for Cancer Research and Cell Biology Queen's University Belfast 97 Lisburn Road Belfast, BT9 7BL

* Principal Investigators can be elected to the committee of the Cancer RRG if they hold national, international or other RDO project grant funding {apply for elected PI status}.